精准检测助力“健康睡眠”

Core Viewpoint - The newly released national standard for the determination of melatonin in health foods, GB/T 45443-2025, will be implemented on October 1, 2025, and aims to optimize detection methods and ensure the quality of melatonin products in the market [1][2]. Group 1: Changes in Standards - The new standard expands the applicable range to include various forms of health food products such as soft capsules, granules, and gel candies, addressing the limitations of the old standard which only covered capsules and tablets [2][3]. - The new standard introduces specialized pre-treatment methods for different product forms, such as a fat removal process for soft capsules and a heating step for gel candies, ensuring accurate detection [3]. Group 2: Detection Methods - A unified method for measuring melatonin content across different forms of health foods has been established, utilizing high-performance liquid chromatography to isolate melatonin from mixed solutions [2]. - The concentration of melatonin must be controlled between 1 to 100 micrograms per milliliter, with a maximum allowable error of 10% for repeated measurements [2]. Group 3: Industry Impact - Experts have praised the new standard for its role in effective regulation, highlighting the use of advanced mass spectrometry technology that enhances sensitivity and specificity in detecting melatonin [3]. - The industry plans to strengthen training and communication regarding the new standard to ensure compliance and improve the quality of melatonin health food products in the market [3].