Workflow
生物医药行业周刊:国内外新药研发稳步推进,各地加码布局生物医药
Chan Ye Xin Xi Wang·2025-06-16 07:23

Group 1 - Eli Lilly's experimental weight loss drug, eloralintide, shows promising results with a maximum weight reduction of 11% over three months and mild side effects [4][5][8] - The study involved 100 participants over 12 weeks, with weight loss ranging from 2.6% to 11.3% [8] - Eli Lilly is exploring the possibility of combining eloralintide with its existing weight loss drug, Zepbound, to enhance treatment efficacy [12][13] Group 2 - AstraZeneca signed a research agreement with CSPC Pharmaceutical Group, valued up to $5.3 billion, to develop therapies for chronic diseases using artificial intelligence [15][19] - This agreement is part of AstraZeneca's strategy to revitalize its business in China, which has faced challenges [16][18] - The collaboration will focus on developing small molecule oral therapies for immune diseases [17] Group 3 - Nuvation Bio announced FDA approval for its ROS1 inhibitor, desatinib, for treating locally advanced or metastatic ROS1-positive non-small cell lung cancer [23] - The drug demonstrates high response rates and good overall tolerability, addressing unmet clinical needs in this treatment area [23] Group 4 - Novo Nordisk plans to initiate Phase III clinical trials for its weight loss drug, amycretin, in Q1 2026, targeting overweight or obese adults [24][25] - Early trial results indicated a weight loss of 22% over 36 weeks for the injectable form and 13.1% for the oral version [25] Group 5 - UroGen Pharma received FDA approval for Zusduri, the first drug approved for treating recurrent low-grade intermediate-risk non-muscle invasive bladder cancer [26][27] - The drug is set to launch in the U.S. on July 1, 2025 [26] Group 6 - Merck's RSV vaccine for infants received FDA approval, allowing the company to launch the drug before the upcoming RSV season [28] - The vaccine is expected to start shipping in July [28] Group 7 - AbbVie announced FDA approval for Mavyret, a direct-acting antiviral for treating acute hepatitis C in children and adults, achieving a cure rate of 96% [29][30] - This is the first DAA therapy approved for treating acute HCV infections within eight weeks [30] Group 8 - Novavax reported strong immune responses from its candidate flu vaccine in adults aged 65 and older, comparable to approved vaccines [31] - The vaccine candidates showed good tolerability without new safety concerns [31] Group 9 - BioNTech announced the acquisition of CureVac for $1.25 billion, enhancing its capabilities in mRNA technology and cancer immunotherapy [32][33] - The deal is expected to be completed by 2025, with CureVac shareholders receiving BioNTech shares [33] Group 10 - The Guangzhou "Leading Enterprises" event focused on connecting capital with the biopharmaceutical industry, featuring various projects seeking funding [35][36] - The event aimed to enhance financial services for private enterprises in the biopharmaceutical sector [36] Group 11 - The Shenyang government is fostering a billion-dollar biopharmaceutical industry cluster, with significant advancements in research and development [46][47] - The city aims to create a highland for innovation and industrialization in the pharmaceutical sector [47] Group 12 - Hubei's biopharmaceutical manufacturing industry reported annual revenue of 123.5 billion yuan, marking a 3.5% increase [48] - The province aims to double its biopharmaceutical revenue to 250 billion yuan by 2027 [48][49] Group 13 - The Suzhou Biopharmaceutical Center hosted a roadshow to accelerate the commercialization of biopharmaceutical technologies from universities [52][53] - The event showcased 32 projects, promoting collaboration between academia and industry [53][55]