先通医药IPO：研发趋于内卷蓝海窗口日益狭窄 递表前已有投资者清仓退出

Core Viewpoint - Xiantong Pharmaceutical is preparing for an IPO on the Hong Kong Stock Exchange, focusing on the development and commercialization of radiopharmaceuticals, but faces significant competition and market challenges [1][2]. Company Overview - Xiantong Pharmaceutical is one of the earliest companies in China engaged in nuclear drug research and development, having previously listed on the New Third Board in 2016 [1]. - The company is the first in China to receive approval for innovative radiopharmaceuticals and has completed clinical trials for therapeutic radioligands [1][2]. Market Position and Competition - The core diagnostic drug, Oweining®, is facing intense competition shortly after its launch, with a narrowing "blue ocean" window [1][4]. - The therapeutic pipeline is crowded with targets such as SSTR and PSMA, with strong competitors like Novartis and Dongcheng [1][7]. - The nuclear pharmacy resources are dominated by major players, controlling 94% of the market, making it difficult for Xiantong to establish its own [1][9]. Financial Performance - In 2023 and 2024, Xiantong achieved revenues of 10.232 million and 44.064 million yuan, respectively, with product sales contributing minimally [3][4]. - The company reported losses of 309 million yuan in 2023 and 156 million yuan in 2024 [3]. Research and Development Pipeline - Xiantong has 15 pipeline assets, with two products, XTR008 and XTR012, expected to receive NDA and ANDA approvals by 2026 [2][5]. - The pipeline includes several diagnostic radiopharmaceuticals, with increasing competition in the domestic market [5][6]. Industry Trends - The global market for radiopharmaceuticals is evolving, with a shift towards therapeutic applications, projected to dominate the market by 2030 [7]. - The construction of nuclear pharmacies is capital-intensive and time-consuming, creating barriers for new entrants [9]. Investor Sentiment - Prior to the IPO application, several investors exited their positions, raising concerns about the company's stability and future prospects [10][11].