病死率几乎100%，广东疾控公布一死亡病例

Core Viewpoint - A recent rabies case in Guangdong resulted in a fatality, highlighting the critical need for timely medical intervention following animal bites [2][3]. Summary by Relevant Sections Rabies Case Details - A patient in Guangdong was bitten by a dog, which died five days later. The patient did not seek medical treatment for the bite and developed symptoms such as fear of water and agitation approximately three months later, leading to coma and eventual death [2]. Rabies Characteristics - Rabies has a nearly 100% fatality rate once symptoms appear, typically resulting in death within 3 to 6 days due to respiratory or circulatory failure [3][5]. - The incubation period for rabies can range from 5 days to several years, with most cases manifesting symptoms within 2 to 3 months [4]. Transmission and Prevalence - Human rabies cases primarily arise from bites or scratches from infected animals, with dogs being responsible for approximately 95% of cases in China [5]. Prevention Measures - It is crucial to maintain distance from unfamiliar animals and avoid provoking them [7]. - Dog owners should ensure their pets are vaccinated, as a vaccination coverage of over 70% in dog populations can effectively interrupt the transmission of the virus [9]. - Immediate and proper treatment is essential if bitten or scratched by an animal, regardless of the severity of the injury [10]. Exposure Classification - Rabies exposure is classified into three levels: - Level I: Contact with animals or intact skin licked, requiring only cleaning [12]. - Level II: Minor bites or scratches needing wound care and vaccination [12]. - Level III: Severe bites or exposure requiring comprehensive treatment including vaccination and immunoglobulin [12]. Treatment Protocols - Proper wound care involves thorough washing with soap and water for at least 15 minutes, followed by disinfection [14]. - Full vaccination must be completed as per the schedule, and any delays can be accommodated without restarting the series [15]. - If the health status of the biting animal is uncertain, vaccination should still be pursued even after several months [16].