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长期规律运动可延缓衰老!我国科学家揭示其中的分子机制
Yang Shi Xin Wen·2025-06-25 20:56

Group 1 - The research reveals that the kidney is a key organ responding to exercise effects, with the metabolite betaine identified as a core molecular messenger for delaying aging [1][5] - The study systematically analyzes the physiological adaptations and mechanisms of acute single exercise versus long-term regular exercise, establishing a multi-dimensional adaptive system based on metabolic reprogramming, immune rejuvenation, epigenetic stability, and enhanced antioxidant capacity [4][5] - Long-term exercise significantly increases kidney betaine levels, and oral intervention with betaine in aged mice extends healthy lifespan and improves five major functional indicators: enhanced metabolic capacity, improved kidney function, better motor coordination, reduced depressive-like behavior, and improved cognitive function [5] Group 2 - The research provides important scientific evidence for promoting healthy aging, opening new pathways for scientific anti-aging research [5] - The study's findings were published in the international academic journal "Cell" on June 25 [1]