甜菜碱是关键！我国研究团队揭示运动延缓衰老分子机制

Core Insights - A Chinese research team has revealed that the kidneys are a key organ in the effects of exercise, with the metabolite betaine acting as a core molecular messenger to delay aging by targeting and inhibiting the natural immune kinase TBK1, thereby alleviating inflammation and multi-organ aging processes [1][2] Group 1: Research Findings - The research, conducted over six years, provides a systematic analysis of the molecular and cellular responses to both acute single exercise and long-term regular exercise [1] - The findings offer cross-scale and cross-species scientific evidence for the positive effects of exercise on health, supporting active health interventions for aging [1] Group 2: Implications for Health and Aging - The study introduces a new paradigm of "endogenous metabolite-mediated exercise benefits," transforming complex physiological effects into quantifiable and operable chemical language [1] - This research lays the groundwork for developing "exercise-mimicking drugs" as a new strategy for systemic aging intervention [1][2]