新型化合物可显著延长线虫寿命

Core Viewpoint - Japanese researchers have developed a compound named proAX that significantly extends the lifespan of nematodes by activating mitochondrial respiration and enhancing cellular energy metabolism [1] Group 1: Compound Development - The compound proAX improves mitochondrial function, which is crucial for synthesizing adenosine triphosphate (ATP), the direct energy source for life activities [1] - The research highlights a scarcity of effective drugs globally that can enhance mitochondrial respiration and increase ATP levels [1] Group 2: Research Findings - Experimental results demonstrate that proAX can significantly prolong the lifespan of laboratory nematodes [1] - The findings have been published in the latest issue of the Journal of the American Chemical Society, indicating a peer-reviewed validation of the research [1] Group 3: Future Research Directions - The research team plans to further evaluate the effects of proAX in mammalian models, such as mice, to assess its potential for broader applications [1]