肠镜是结直肠癌筛查“金标准”但仍会漏诊，国产技术寻找突破口

Core Viewpoint - The study led by Shanghai Jiao Tong University Affiliated Renji Hospital demonstrates that the novel spectral imaging technology significantly improves the detection rate of colorectal adenomas compared to traditional white light endoscopy, addressing the challenge of missed diagnoses in flat lesions [1][4]. Group 1: Colorectal Cancer Context - Colorectal cancer is the second most prevalent and the fourth leading cause of cancer-related deaths in China [1]. - Approximately 90% of colorectal cancers arise from adenomas, and early removal can increase the five-year survival rate to over 90% [3]. Group 2: Study Overview - The multi-center randomized controlled trial involved over 698 patients across various regions in China, comparing the adenoma detection rates (ADR) of spectral imaging technology (SFI) and traditional white light endoscopy [1][4]. - The study is the first large-scale investigation of domestic spectral imaging technology in China, lasting nearly one year [1]. Group 3: Results of the Study - The adenoma detection rate for spectral imaging technology was 38.29%, significantly higher than the 30.46% rate for white light endoscopy, with statistical significance [4]. - Secondary outcomes showed that the polyp detection rate, flat serrated lesions detection rate, and advanced adenoma detection rate for spectral imaging were 56.29%, 3.14%, and 6.57%, respectively, all higher than the corresponding rates for white light endoscopy [4]. Group 4: Technological Advantages - Spectral imaging technology enhances the contrast between lesions and normal mucosa, making it easier to identify flat lesions and flat serrated lesions that are often missed with white light endoscopy [4]. - The technology is designed to be user-friendly, allowing for easy switching between imaging modes without the need for dye application, thus reducing the reliance on clinical experience [5].