人脑解码倒计时 中国团队正在绘制大脑“地图”

Group 1 - The core achievement of the research is the development of a three-dimensional reconstruction of 2,231 projection neurons in the macaque prefrontal cortex, revealing a "streamlined and efficient" connectivity pattern akin to a precise circuit for modular information processing [1] - The research team from the Chinese Academy of Sciences has developed an imaging system capable of completing whole-body subcellular resolution imaging of adult mice in 40 hours, clearly presenting the projection pathways of peripheral nerve fibers [1] - A new cell-type-specific targeting tool for primate brain research has been developed, overcoming transgenic limitations and marking a new stage in precise cell type analysis in macaque brains [1] Group 2 - The "Whole Brain Mesoscopic Neural Connectivity Atlas" project aims to create a comprehensive research system from circuit analysis to disease decoding, with a focus on mapping the mesoscopic brain atlas of non-human primates [2] - An international primate brain atlas research alliance is being established to integrate multinational technological resources and create a shared database, ultimately aiming to "understand, simulate, and protect the brain" [2] - The research team is continuously optimizing surgical techniques for macaque brain injections, which require precise navigation to avoid blood vessels and functional areas, highlighting the complexity and dedication involved in the procedures [2] Group 3 - The Chinese Brain Project aims to conduct large-scale foundational research while also addressing major societal needs through the diagnosis and treatment of brain diseases, as well as developing brain-machine interfaces and brain-inspired artificial intelligence [3] - The recent breakthroughs in brain mapping technology are expected to clarify brain structures and inspire research in brain-like intelligence [4] - A global open-access brain atlas database has been established, integrating cross-species cell atlases, neural connectivity maps, and multimodal dynamic data, which will support future understanding of human brain functioning and the development of next-generation brain-inspired AI [4]