桃多组学数据库发布，全流程覆盖基因挖掘到分子设计

Core Viewpoint - The PeachMD database, developed by the Peach genetic breeding team at the Zhengzhou Fruit Research Institute of the Chinese Academy of Agricultural Sciences, integrates multiple omics data for peach, providing significant support for molecular breeding and functional genomics research [1][4]. Group 1: Database Features - PeachMD is the first database to integrate peach genome, epigenome, population genetic variation, and multidimensional phenotype data [1][4]. - The database includes 12 published peach genomes, 329 transcriptome datasets, 102 whole-genome bisulfite sequencing data, and 1313 whole-genome resequencing data, covering key agronomic traits [4][5]. - It supports CRISPR design and GWAS analysis tools, facilitating a comprehensive approach from gene mining to molecular design [5]. Group 2: Technological Advancements - The rapid development of high-throughput sequencing technology and the significant reduction in sequencing costs have led to an exponential increase in biological big data [3]. - The accumulation of multi-omics data presents unprecedented opportunities for understanding peach evolution and identifying key genes for important traits [4]. Group 3: Challenges and Solutions - The main challenge faced by researchers is the efficient integration and deep mining of complex multi-omics data to extract valuable biological information [4]. - The establishment of multi-omics databases like PeachMD is crucial for advancing peach genetic breeding research [4].