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上海复星医药(集团)股份有限公司关于控股子公司签订许可协议的公告
Shang Hai Zheng Quan Bao·2025-07-28 18:57

Core Viewpoint - The announcement details a licensing agreement between Fosun Pharma and NewCo for the development, registration, production, and commercialization of the drug AR1001, aimed at treating Alzheimer's disease and other neurological disorders in China and Hong Kong [2][4][20]. Group 1: Agreement Overview - The agreement allows Fosun Pharma's subsidiary to develop and commercialize AR1001, which is currently undergoing Phase III clinical trials globally, including in China [7][8]. - The licensing agreement does not require approval from the company's board or shareholders [5]. - The agreement is not classified as a related party transaction [6]. Group 2: Product Details - AR1001 is an oral drug designed to slow the progression of Alzheimer's disease, with strong PDE-5 inhibition properties [7]. - Clinical trials have shown that AR1001 can clear amyloid plaques associated with Alzheimer's and has potential therapeutic effects for early-stage patients [7]. Group 3: Financial Terms - Fosun Pharma will pay up to RMB 150 million (approximately $22 million) to NewCo, including an upfront payment of RMB 40 million and milestone payments based on regulatory progress [12]. - For localized products, Fosun Pharma will pay a tiered sales milestone based on annual net sales, with a low double-digit percentage sales share to NewCo [12]. Group 4: Strategic Impact - This collaboration aims to enhance Fosun Pharma's product pipeline in the central nervous system field, improving its market position and competitiveness in treating Alzheimer's and other neurological diseases [20].