夜间痒到睡不着？北大人民医院教授教你科学应对特应性皮炎

Core Insights - The article discusses the confusion between atopic dermatitis (AD) and eczema, highlighting that AD is a specific type of eczema with distinct characteristics [1] - It emphasizes the prevalence of AD in China, with over 70 million patients, and the common misconceptions surrounding the disease [1] - The article outlines the importance of proper diagnosis and treatment methods for managing AD effectively [2][4] Group 1: Disease Understanding - Atopic dermatitis is characterized by chronic inflammation, severe itching, and recurrent episodes, with about 60% of patients also suffering from allergic rhinitis or asthma [1] - The disease has a significant familial aggregation, with a 50% chance of children developing AD if one parent is affected [1] - The "Zhang's criteria" for diagnosis requires meeting two out of three conditions: chronic or recurrent symmetrical eczema, personal or family history of allergies, and elevated serum IgE or eosinophils [1] Group 2: Treatment Approaches - The "three-dimensional anti-itch method" includes cold compresses, moisturizing creams, and medication, with innovative topical agents like Zeli Mei showing promising results [2] - Clinical data indicates that 61.5% of patients in an 8-week trial achieved complete clearance of skin lesions, with rapid itch relief observed within 2 hours [2] - The drug is priced significantly lower in China at 360 yuan compared to 1,400 USD in the U.S., easing the financial burden on patients [2] Group 3: Long-term Management - Active maintenance treatment is crucial, with recommendations for preventive use of Zeli Mei even after symptoms disappear, reducing the risk of recurrence by 60% [4] - Keeping a "itch diary" to track triggers such as temperature and diet is advised for better management of the condition [4] - The drug has been approved for use in children over 2 years old, showing over 80% clearance rate in clinical trials with minimal side effects [4]