Palisade Bio Receives Notice of Allowance for Composition of Matter Patent Covering Lead Product Candidate PALI-2108 in China

Core Insights - PALI-2108 is the first and only PDE4 inhibitor specifically designed to target the terminal ileum and colon for treating fibrostenotic Crohn's disease (FSCD) and ulcerative colitis (UC), addressing significant unmet medical needs in these conditions [1] - The inflammatory bowel disease market in China is projected to approach $1 billion in total revenues by 2030, indicating a large and growing market opportunity [1] Company Developments - The China National Intellectual Property Administration has issued a Notice of Allowance for a patent covering PALI-2108, with a base patent term extending into 2045, subject to regulatory approval extensions [2] - The CEO of Palisade Bio emphasized the importance of strengthening the global intellectual property portfolio for PALI-2108, which supports the company's clinical and strategic objectives in one of the fastest-growing pharmaceutical markets [3] - Palisade Bio is currently conducting a Phase 1b/2a clinical trial for PALI-2108 aimed at treating FSCD and UC, with multiple near-term clinical milestones expected in the next 12-18 months [3] Company Overview - Palisade Bio is a clinical-stage biopharmaceutical company focused on developing novel therapeutics for patients with autoimmune, inflammatory, and fibrotic diseases, aiming to transform the treatment landscape through targeted approaches [4]