Mei Ri Jing Ji Xin Wen·2025-08-07 02:36Core Insights - Heng Rui Medicine (600276) has announced a significant agreement with pharmaceutical giant GlaxoSmithKline (GSK), granting GSK global rights to a core drug and 11 early-stage projects, with an initial payment of $500 million and a potential total value of up to $12.5 billion, setting a new record for single BD transactions in China's innovative drug sector [1][1][1] Group 1 - The collaboration employs a "core product + pipeline option" model, allowing GSK to choose from 11 early-stage projects covering oncology, autoimmune diseases, and inflammation, in addition to HRS-9821 [1][1] - Heng Rui will lead the development of these projects through to the completion of Phase I clinical trials involving overseas participants, after which GSK can opt to exercise exclusive global development and commercialization rights [1][1] - Each project will have an independent financial structure, with Heng Rui potentially receiving $12 billion in milestone payments and tiered sales royalties if all projects succeed [1][1][1] Group 2 - The Hong Kong Stock Connect Medical ETF (520510) has been launched, tracking the Hong Kong Stock Connect Medical Theme Index, which encompasses three major segments of the medical sector [1][1] - The index has over 30% weight in CXO, more than 20% in AI medical applications, and nearly 50% in innovative drugs, positioning it to benefit from trends such as anti-involution, the internationalization of innovative drugs, and the AI technology revolution [1][1][1]