WANTAI BIOLOGICAL(SH:603392) Xin Hua Wang·2025-08-12 05:44Core Points - The first domestically produced nine-valent HPV vaccine "Xinkening®9" is priced at 499 yuan per dose, approximately 40% of the price of imported nine-valent HPV vaccines, marking the end of the "high-price era" for HPV vaccines [1] - The vaccine was developed by a team led by Academician Xia Ning Shao from Xiamen University and Wantai Biological Pharmacy, utilizing a novel prokaryotic expression system [2] - The development process took 18 years and involved over 1 million independent trials, showcasing a significant increase in complexity compared to the two-valent HPV vaccine [2][3] - Clinical trial results published in The Lancet Infectious Diseases indicate that "Xinkening®9" has similar immune response and safety profiles to imported vaccines, effectively preventing high-risk HPV infections [3] - The vaccine is the only one approved for a two-dose regimen for ages 9-17, which may significantly improve vaccination compliance among young girls in China [4] Industry Insights - The nine-valent HPV vaccine not only retains the protective effects against HPV16 and HPV18 but also covers additional high-risk types, achieving over 98% protection against related persistent infections [5] - The collaboration between Wantai Biological and Xiamen University represents a successful model of industry-academia integration, having completed numerous national-level research projects [6] - Wantai Biological has invested approximately 1 billion yuan in the development of the nine-valent HPV vaccine, reflecting a strong commitment to research and innovation [6][7] - The introduction of a cost-effective HPV vaccine is expected to enhance vaccination rates among eligible women in China, contributing to the global goal of cervical cancer elimination [7]