Athira Pharma(US:ATHA) Globenewswireยท2025-08-14 11:00Core Insights - Athira Pharma, Inc. presented results from its Phase 1 clinical trial of ATH-1105 at the ALS Nexus 2025 conference, focusing on developing treatments for neurodegenerative diseases like ALS [1][3] - ATH-1105 is a novel, orally available small molecule designed to modulate the neurotrophic HGF system, potentially offering new treatment options for ALS [2][3] Group 1: Clinical Trial Results - The Phase 1 trial of ATH-1105 involved 80 healthy volunteers and evaluated the safety, tolerability, and pharmacokinetics of the drug, showing a favorable safety profile and good tolerability [5] - Results indicated dose-proportional pharmacokinetics and CNS penetration, supporting the continued development of ATH-1105 [3][5] Group 2: Company Overview - Athira Pharma is a clinical-stage biopharmaceutical company based in the Seattle area, focused on developing small molecules to restore neuronal health and slow neurodegeneration [6] - The company aims to alter the course of neurological diseases through its pipeline of drug candidates targeting the neurotrophic HGF system [6]