浙江省首例胃癌加压腹腔气溶胶化疗成功实施！ 晚期胃癌腹膜转移患者迎来治疗新曙光

Core Viewpoint - The successful implementation of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) for a patient with gastric cancer peritoneal metastasis marks a significant advancement in treatment options for late-stage cancer patients in Zhejiang Province, providing a new international standard of care [1][6]. Group 1: Patient Case - A 60-year-old male patient, referred to as Liu, was diagnosed with gastric cancer and peritoneal metastasis, experiencing severe symptoms including significant weight loss and abdominal swelling [2][3]. - Traditional treatment options were limited for Liu due to the advanced stage of his cancer, prompting his family to seek out advanced treatment at Zhejiang Provincial Cancer Hospital [2][4]. Group 2: PIPAC Treatment Details - The PIPAC procedure involved creating a high-pressure environment in the abdominal cavity and delivering chemotherapy in aerosol form, allowing for uniform distribution of the drug to tumor sites [3][4]. - The treatment was completed in approximately one hour, and Liu experienced rapid recovery, reporting reduced abdominal swelling and improved overall well-being shortly after the procedure [3][4]. Group 3: Advantages of PIPAC - PIPAC offers significant advantages over traditional chemotherapy methods, including higher drug concentration at tumor sites and reduced systemic side effects, with the dosage being only one-tenth of that used in intravenous chemotherapy [4][5]. - This method is particularly beneficial for patients like Liu, who are physically weak and unable to tolerate aggressive treatments, and allows for repeat treatments every 4-8 weeks with real-time assessment of effectiveness [4][5]. Group 4: Institutional Impact - The successful application of PIPAC at Zhejiang Provincial Cancer Hospital represents a breakthrough in the treatment of gastric cancer, positioning the institution as a leader in the field [5][6]. - The hospital's focus on international clinical outcomes and two years of preparation led to this pioneering achievement in the province, potentially benefiting many patients suffering from peritoneal metastasis in the future [5][6].