Core Viewpoint - Shenzhen Chipscreen Co., Ltd. is preparing for a specific issuance of A-shares in 2024, with the underwriting by Guotou Securities, emphasizing its commitment to compliance and due diligence in the process [1][2]. Company Overview - Shenzhen Chipscreen Co., Ltd. was established on March 21, 2001, with a registered capital of 408.54 million yuan and is listed on the Shanghai Stock Exchange's Sci-Tech Innovation Board under the stock code 688321 [5]. - The company focuses on providing affordable, clinically needed innovative drugs, with a complete capability from drug discovery to commercialization [3]. Main Business - The company has products in commercialization, with core pipelines undergoing global registration clinical trials. Its main products include: - Westabamine: Approved for multiple cancers in China, Japan, and Taiwan, recognized as a first-line treatment for certain lymphomas [4][7]. - Sigraglitazone: Approved for Type 2 diabetes and included in medical insurance, with plans to promote its unique advantages in metabolic disease management [4][17]. Research and Development - The company has a robust R&D team of 272 personnel, with a high percentage holding advanced degrees, focusing on innovative drug discovery [5]. - As of March 31, 2025, the company holds 191 authorized invention patents, ensuring a comprehensive global patent strategy to protect its products [6]. Financial Data - As of March 31, 2025, the total assets of the company amounted to 3.31 billion yuan, with total liabilities of 1.75 billion yuan and equity attributable to shareholders of 1.56 billion yuan [23]. - For the first quarter of 2025, the company reported an operating income of 162.26 million yuan, with a net profit attributable to shareholders of -19.15 million yuan [23]. Clinical Trials and Product Pipeline - The company is advancing several clinical trials, including: - Westabamine: Involved in multiple Phase III trials for various cancers, showing promising results in combination therapies [12][14]. - Sigraglitazone: Demonstrated significant efficacy in controlling blood sugar levels and improving lipid metabolism in Type 2 diabetes patients [18][19]. - Xiaoroni: A multi-target kinase inhibitor currently in clinical trials for pancreatic and ovarian cancers [20][21]. Market Position and Strategy - The company aims to transform "cold tumors" into "hot tumors" to enhance immunotherapy responses, positioning itself strategically in the oncology market [15]. - Collaborations with international partners for global development and commercialization of its products are underway, marking a significant step in expanding its market reach [16].
微芯生物: 国投证券股份有限公司关于深圳微芯生物科技股份有限公司向特定对象发行股票之上市保荐书