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Minovia Therapeutics Announces $350,000 Grant from Countdown for a Cure Foundation to Develop Mitochondria Blood-Based Biomarkers

Company Overview - Minovia Therapeutics Ltd. is a clinical-stage biotechnology company focused on developing therapies for mitochondrial diseases and age-related decline [1][5] - The company is working on its main drug product, MNV-201, which is currently being tested for Pearson Syndrome and Myelodysplastic Syndrome [5] Recent Developments - Minovia has been awarded a $350,000 grant from Countdown for a Cure to develop novel mitochondrial blood-based biomarkers [1][2] - The grant will fund clinical operations for blood sample collection from approximately 30 patients with primary mitochondrial diseases and 140 samples from healthy controls [2] Research and Development - The company aims to develop blood-based functional mitochondrial biomarkers to identify patients who may benefit from its proprietary mitochondrial augmentation technology (MAT) [2] - A clinical trial has been initiated at Sheba Medical Center to collect blood samples for analysis and to determine a "MitoScore" for each sample [2] Market Need - Mitochondrial dysfunction is associated with rare genetic mitochondrial diseases and chronic age-related diseases, with a significant unmet need for effective treatments [3] - Currently, there are no approved therapies for mitochondrial dysfunction, nor functional tests to diagnose and quantify it [3] Business Combination - Minovia has entered into a definitive business combination agreement with Launch One Acquisition Corp., a publicly traded special purpose acquisition company [4] - The transaction is expected to close in late 2025, after which the combined company will operate as Minovia Therapeutics and trade on Nasdaq under a new ticker symbol [4]