压力会在分子层面改变心脏功能

Core Insights - A new study from the University of California, Davis reveals that stress affects not only the brain but also alters heart function at the molecular level [1] - The research focuses on environmental and social stressors, such as noise, crowding, and sleep disruption, and their impact on cardiovascular health, particularly how chronic psychological stress contributes to the development of cardiovascular diseases [1] Summary by Categories Research Findings - Animal experiments showed that just 10 days of acute stress can trigger inflammation, leading to subtle changes in heart function [1] - The study identified the activation of a multi-protein complex known as NLRP3 inflammasome, which acts as a key "amplifier" in the inflammatory response [1] - It is the first time scientists have confirmed that environmental stress can directly initiate this process within heart cells, releasing harmful molecules that promote heart disease [1] Implications for Health - While lifestyle changes and stress reduction are ideal for heart protection, these may be challenging for individuals living in high pollution, high noise, or high social stress environments [1] - The research team aims to identify intervenable targets based on this mechanism to pave the way for new therapies [1] - Future plans include investigating how chronic stress affects the "brain-heart axis" and its impact on gut microbiota and systemic chemical environments [1] - Collaboration with clinicians is planned to translate these findings into practical treatment options to help patients alleviate cardiac stress [1]