道指开盘跌0.97%，标普500跌1.3%，纳指跌1.7%

Group 1 - PepsiCo shares increased by 5.8%, with activist investment firm Elliott Management holding $4 billion in shares [1] - Cytokinetics shares surged by 27.2% following significant efficacy results from clinical trials of aficamten in treating symptomatic obstructive hypertrophic cardiomyopathy patients [1] - Constellation Brands shares fell by 7.3% after the company lowered its full-year earnings guidance [1] - Beike shares rose by 2.1%, with multiple institutions reaffirming a "buy" rating post-earnings [1]