Zheng Quan Zhi Xing·2025-09-03 16:19Core Viewpoint - The report outlines the ongoing supervision and financial performance of Hai Chuang Pharmaceutical Co., Ltd., highlighting its focus on innovative drug development in oncology and metabolic diseases, while also addressing the associated risks and challenges in achieving profitability and market acceptance [1][2][3]. Group 1: Continuous Supervision and Financial Performance - The continuous supervision by CITIC Securities has not revealed any major issues within the company during the reporting period [2]. - The company reported a revenue of 13.17 million yuan for the first half of 2025, with a net loss of 61.85 million yuan, indicating ongoing financial challenges [2][11]. - Research and development expenses for the period amounted to 56.97 million yuan, reflecting a significant investment in drug development [8][20]. Group 2: Risks and Challenges - The company faces risks related to its lack of profitability, as it is heavily invested in R&D with long timelines for product commercialization [2][3]. - There is a risk of significant revenue decline or losses due to ongoing R&D expenditures and the uncertain approval timelines for new drugs [2][3]. - The company’s core product, Deuterated Enzalutamide soft capsules, was approved for sale in May 2025, but the commercial success remains uncertain due to competition and market acceptance challenges [5][11]. Group 3: R&D and Product Pipeline - The company has established four core technology platforms, including PROTAC and deuterated drug development, which are crucial for its innovative drug pipeline [13][19]. - The Deuterated Enzalutamide soft capsule is the first domestically approved drug for treating metastatic castration-resistant prostate cancer, marking a significant milestone for the company [13][21]. - The company is actively pursuing clinical trials for multiple products, including HP518, which has received fast-track designation from the FDA for treating AR-positive triple-negative breast cancer [15][22]. Group 4: Fundraising and Financial Management - The total amount raised through public offerings was approximately 1.06 billion yuan, with a significant portion already utilized for R&D and operational expenses [26]. - As of June 30, 2025, the company had a remaining balance of 117.24 million yuan in its fundraising account, indicating ongoing financial management efforts [26][27]. - The company has implemented a structured approach to manage and utilize the raised funds effectively, ensuring compliance with regulatory requirements [26].