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浙江莎普爱思药业股份有限公司 关于全资子公司获得盐酸毛果芸香碱滴眼液临床试验批准通知书的公告

Group 1 - The core point of the announcement is that Zhejiang Shapuaisi Pharmaceutical Co., Ltd.'s wholly-owned subsidiary has received approval for clinical trials of a new eye drop medication, which is intended for the treatment of presbyopia in adults [1][2]. - The drug, named Pilocarpine Hydrochloride Eye Drops, is classified as a Class 3 chemical drug and is currently in the clinical trial phase [1][3]. - The total research and development investment for the Pilocarpine Hydrochloride Eye Drops project has reached approximately 6.4457 million RMB [3]. Group 2 - The major shareholder, Mr. Chen Dekang, holds 43,871,004 shares, accounting for 11.67% of the total share capital of the company [7]. - Mr. Chen plans to reduce his holdings by up to 3,759,250 shares through centralized bidding and another 3,759,250 shares through block trading, totaling a maximum of 7,518,500 shares, which is 2.00% of the total share capital [7][8]. - The reduction plan is due to personal financial needs and will take place from September 25, 2025, to December 24, 2025 [7].