推动合作共享！“十万长读长大人群联盟”在深圳宣布成立

Core Insights - The "Long 100K Genomes Consortium" was officially established to integrate long-read sequencing technology resources and enhance high-precision genetic structure analysis capabilities [1][2] - The consortium aims to promote the application of long-read sequencing technology across various fields, including research, clinical settings, agriculture, and drug development [1][2] Group 1: Consortium Formation and Objectives - The consortium consists of 18 initial members, including universities, hospitals, research institutions, and companies, highlighting a collaborative effort in advancing long-read sequencing technology [2] - The alliance will focus on standardization, data sharing mechanisms, and expanding applications across multiple fields to strengthen China's competitive position in global population genetics research [2] Group 2: Technological Advancements and Applications - The G400-ER sequencing platform has demonstrated a data output exceeding 400GB per chip and an accuracy rate of Q17+ (≥98%), showcasing the technological capabilities of the consortium members [3] - The consortium plans to create a comprehensive genetic structure map of the Chinese population, establishing a new paradigm for precision medicine through resource sharing and collaborative efforts [3] Group 3: Clinical Integration and Research Collaboration - Long-read sequencing technology is transitioning from development to clinical maturity, addressing challenges in pathogen detection and complex disease diagnosis [4] - Experts emphasize the importance of ethical review and compliance with national policies in conducting cohort studies, advocating for a combination of long-read and short-read sequencing technologies for optimal results [5] Group 4: Future Directions and Strategic Goals - The establishment of the consortium is seen as a critical opportunity for the transition of long-read sequencing technology from research to clinical applications, with expectations for resource integration and efficiency enhancement [5] - The consortium aims to foster collaboration among various stakeholders to drive advancements in life sciences, precision medicine, and industry transformation, contributing to human health and societal development [5]