我科研团队刷新磷脂酰丝氨酸合成效率纪录

Core Insights - The research team from the Chinese Academy of Agricultural Sciences has developed a high-performance immobilized phospholipase, achieving a world record in the synthesis efficiency of phosphatidylserine, a key functional phospholipid [1][2] - Phosphatidylserine is essential for brain health, playing a significant role in improving symptoms of Alzheimer's disease, brain injury repair, memory enhancement, and mood improvement [1] - The demand for phosphatidylserine is rapidly increasing due to the expanding market for nutritional supplements, functional foods, and health products [1] Summary by Sections - Research Development - The team successfully created a highly active and specific immobilized phospholipase, significantly enhancing enzyme stability and reusability [2] - A unique Pickering interface biocatalysis system was constructed, utilizing solid particles to form a stable interfacial film at the oil-water interface, promoting efficient contact and reaction between the enzyme and substrate [2] - Performance Metrics - The new biocatalysis system achieved a conversion rate of 93.8% for phosphatidylserine within just 20 minutes, with a concentration of up to 40 grams per liter of reaction solvent [2] - Industry Implications - This breakthrough technology addresses the challenges of industrializing enzyme synthesis of phosphatidylserine, significantly improving production efficiency and reducing costs [2] - It also provides new technological ideas and tools for the green biomanufacturing of other high-value functional lipids [2]