Schaeffers Investment Researchยท2025-09-22 15:08Group 1 - Pfizer Inc (NYSE:PFE) stock increased by 2.6% to $24.65 following the announcement of its acquisition of weight-loss drug company Metsera (MTSR) for up to $7.3 billion [1] - The stock is experiencing its best single-day percentage gain since July and has gained in three of the last four sessions, although it faces resistance at the $25 level after a pullback in late August [1] - Over the past 12 months, PFE's stock has decreased by 16.5% [1] Group 2 - Options trading activity for PFE has surged, with 115,000 calls traded, which is four times the average intraday volume, compared to only 17,000 puts [2] - New positions are being opened at the most active contracts, specifically the October 25 and 9/26 24.50 calls [2] Group 3 - The 50-day call/put volume ratio for PFE is 2.72, indicating that options traders are significantly more bullish than usual, ranking higher than 82% of readings from the past year [3] - The Schaeffer's Volatility Index (SVI) for PFE is at 23%, placing it in the 5th percentile of its annual range, suggesting that options traders are anticipating low volatility [4]