Globenewswire·2025-09-24 05:00Core Insights - Lantheus Holdings and GE HealthCare have entered into an exclusive licensing agreement for the development, manufacturing, and commercialization of piflufolastat F18 (PYLARIFY) in Japan for prostate cancer diagnostics [1][2] - The partnership aims to enhance the reach of PYLARIFY in international markets, particularly in Japan, which has the third highest number of prostate cancer cases globally [3][4] - GE HealthCare will leverage its manufacturing network and R&D expertise, especially following its acquisition of Nihon Medi-Physics Co., Ltd. in March 2025 [2][3] Company Overview - Lantheus is a leading radiopharmaceutical-focused company, providing solutions for nearly 70 years, with a mission to improve patient outcomes through innovative diagnostics [19] - GE HealthCare is a global healthcare solutions provider with a focus on medical technology and pharmaceutical diagnostics, serving patients and providers for over 125 years [20] Product Information - PYLARIFY is a PSMA-targeted PET imaging agent approved by the FDA in 2021, and it has been utilized in over 500,000 scans across the U.S. [4] - The product is designed to visualize lymph nodes, bone, and soft tissue metastases in men with prostate cancer, combining the accuracy of PET imaging with the precision of PSMA targeting [5] Financial Terms - Under the agreement, GE HealthCare will pay Lantheus an upfront license fee, development milestones, and tiered royalties based on product sales in Japan [2][3]