康华生物股价涨5.18%，南方基金旗下1只基金位居十大流通股东，持有86.17万股浮盈赚取327.45万元

Group 1 - The core viewpoint of the news is that Kanghua Biological has seen a significant increase in its stock price, rising by 5.18% to 77.22 yuan per share, with a total market capitalization of 10.034 billion yuan [1] - Kanghua Biological, established on April 2, 2004, specializes in the comprehensive research, development, and operation of vaccines, with 99.99% of its main business revenue coming from non-immunization planning vaccines [1] - The trading volume for Kanghua Biological reached 190 million yuan, with a turnover rate of 2.13% [1] Group 2 - Among the top circulating shareholders of Kanghua Biological, the Southern Fund's Southern CSI 1000 ETF (512100) has recently entered the top ten, holding 861,700 shares, which accounts for 0.71% of the circulating shares [2] - The Southern CSI 1000 ETF has achieved a year-to-date return of 27.39% and a one-year return of 61.83%, ranking 2082 out of 4220 and 1362 out of 3824 in its category, respectively [2] - The fund manager of Southern CSI 1000 ETF, Cui Lei, has been in position for 6 years and 325 days, with the fund's total asset size reaching 94.976 billion yuan [3]