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康辰药业(603590.SH):KC1036联合PD-1抗体和含铂化疗一线治疗晚期复发或转移性食管鳞癌获得临床试验通知书

Core Viewpoint - Kangchen Pharmaceutical (603590.SH) has received approval from the National Medical Products Administration for clinical trials of its innovative chemical drug KC1036, aimed at treating advanced recurrent or metastatic esophageal squamous cell carcinoma in combination with PD-1 antibodies and platinum-based chemotherapy [1] Group 1: Product Development - KC1036 is a self-developed innovative chemical drug with global intellectual property rights held by the company [1] - The drug exhibits anti-tumor activity by inhibiting multiple targets such as VEGFR2 and AXL, demonstrating strong vascular targeting and tumor cell growth suppression [1] - Clinical studies for KC1036 are ongoing for various indications, including gastrointestinal tumors, thymic tumors, and pediatric Ewing sarcoma, with over 300 subjects enrolled to date [1] Group 2: Clinical Trial Results - Preliminary clinical research results indicate significant anti-tumor activity, along with good safety and tolerability profiles for KC1036 [1]