STRATA Skin Sciences Receives Continued Validation for its Personalized Approach with New Published Study Highlighting XTRAC® Excimer Laser Treatment Combined with a Topical Drug in Psoriasis

Core Insights - STRATA Skin Sciences, Inc. has published a peer-reviewed study demonstrating the efficacy of its XTRAC 308nm Excimer Laser combined with 0.1% tacrolimus ointment for treating plaque-type psoriasis, showing significant improvement over topical monotherapy [1][2][3] Study Design and Findings - The study involved 100 adult patients with plaque-type psoriasis, divided into a control group receiving only tacrolimus and an observation group receiving both tacrolimus and Excimer laser therapy [3] - Key findings indicate that the observation group experienced a mean PASI reduction from 18.36 to 3.30, while the control group saw a reduction from 18.62 to 5.23, with a statistically significant difference (p < 0.01) [6] - The study highlights the safety profile, reporting no serious adverse events and only mild, self-resolving irritations in a few patients [6] Mechanism and Personalization - The combination therapy works through complementary immunomodulatory pathways, enhancing patient outcomes by targeting pathogenic T-cells and suppressing keratinocyte hyperproliferation [6] - Individualized dosing based on Minimum Erythema Dose (MED) allows for targeted treatment of lesions, maximizing benefits while minimizing exposure to healthy tissue [6] Strategic Implications - The study reinforces STRATA's leadership in personalized dermatologic care, supporting the use of Excimer laser in conjunction with topical agents and other therapies [5] - STRATA's President and CEO emphasized the importance of this study in advocating for expanded reimbursement from CMS, as demand for non-biologic treatment options grows [4] Company Overview - STRATA Skin Sciences is focused on developing innovative products for dermatologic conditions, including psoriasis, vitiligo, and acne, with offerings such as the XTRAC excimer laser and VTRAC lamp systems [7] - The company employs a unique Partnership Program to provide its technologies, which includes a fee per treatment cost structure and comprehensive support for practices [8]