Halozyme eyes microparticles in $900m Elektrofi acquisition

Core Viewpoint - Halozyme Therapeutics is acquiring Elektrofi for up to $900 million to enhance its drug delivery technology portfolio, specifically adding microparticle capabilities [1] Group 1: Acquisition Details - The acquisition includes an upfront payment of $750 million and three milestone payments of $50 million each, contingent on the approval of three undisclosed products [1] - Halozyme's acquisition aims to expand its offerings in subcutaneous drug delivery technologies [4] Group 2: Technology and Benefits - Elektrofi's platform, Hypercon, allows for biologic concentrations up to five times higher than standard formulations, enabling high protein concentrations while maintaining subcutaneous administration [2] - The new auto-injector technology from Elektrofi can reduce injection volume for the same dosage, creating more opportunities for administration in healthcare settings and at home [3] Group 3: Market Position and Financial Performance - Halozyme's revenue grew by 22% to over $1 billion in 2024, driven by its Enhanze subcutaneous drug delivery technology [5] - The business models of both Halozyme and Elektrofi are similar, focusing on royalty revenue, with Elektrofi's patents extending into the 2040s, supporting long-term revenue growth [6] Group 4: Future Prospects - Halozyme expects that two of Elektrofi's partner products will enter clinical development by the end of 2026, with potential royalties starting as early as 2030 [7] - There is a potential of up to $275 million in development and commercial milestone payments linked to these two products, which include de-risked mechanisms of action that are already approved blockbusters [7]