Bristol-Myers Squibb, Takeda, Astex Join AI Consortium to Train OpenFold3 for Accelerated Drug Discovery

Group 1 - Bristol-Myers Squibb, Takeda Pharmaceuticals, and Astex Pharmaceuticals have formed a collaboration to utilize AI for drug discovery by pooling proprietary data [1][3] - The collaboration will contribute data from several thousand experimentally determined protein-small molecule structures to train an AI model named OpenFold3 [2][3] - The initiative employs a federated data sharing model provided by Apheris, allowing secure aggregation of diverse datasets while keeping sensitive data in its original location [2][3] Group 2 - The goal of the initiative is to enhance the accuracy of OpenFold3 in predicting interactions between proteins and small molecules, which is vital for drug discovery and development [3] - OpenFold3 is part of the AI Structural Biology Network, conducted in collaboration with the AlQuraishi Lab at Columbia University [3]