Core Viewpoint - Binhui Biotech has submitted a listing application to the Hong Kong Stock Exchange, with Huatai International, CMB International, and Bank of China International as joint sponsors [1] Company Overview - Binhui Biotech is a biotechnology company focused on the discovery, development, and commercialization of cancer immunotherapy, specifically on oncolytic virus therapy [1] - The company's lead product, BS001 (OH2 injection), is an oncolytic virus candidate based on type II herpes simplex virus (HSV-2) that selectively replicates in tumor cells and activates systemic immunity [1] Product Development - BS001 is the first oncolytic virus candidate based on HSV-2 to reach clinical stage and enter Phase III pivotal trials globally, currently undergoing a Phase III clinical trial for melanoma in China [1] - BS001 has received orphan drug designation from the FDA for the treatment of stage III-IV melanoma and malignant glioma, as well as fast track designation for treating refractory or progressive melanoma [1] - In a Phase Ia/Ib trial, BS001 demonstrated a median overall survival of 31.06 months, with an objective response rate of 34.48%, and up to 42.1% in patients resistant to PD-1 therapy [1] Leadership and Expertise - The company is led by Dr. Liu Binlei, who has over 30 years of experience in tumor immunology and oncolytic virology, and was a core member of the development team for the FDA-approved oncolytic virus drug IMLYGIC® (T-VEC) [1]
滨会生物递表港交所 华泰国际、招银国际和中银国际为联席保荐人
Zheng Quan Shi Bao Wang·2025-10-09 00:31