百利天恒子公司与百时美施贵宝合作协议触发里程碑付款条件
Zheng Quan Shi Bao Wang·2025-10-12 11:56

Core Insights - 百利天恒 has secured a significant collaboration with Bristol-Myers Squibb (BMS) for the drug izabren, receiving an upfront payment of $800 million and potential milestone payments totaling up to $7.1 billion [1] - The company has received approval for its innovative drug BL-ARC001, which utilizes advanced targeted delivery technology for enhanced tumor specificity and efficacy [2] - 百利天恒 successfully raised 3.764 billion yuan through a private placement to accelerate its drug development pipeline, particularly in the ADC and multi-specific antibody platforms [3] Group 1 - 百利天恒's subsidiary SystImmune entered into an exclusive licensing agreement with BMS for the drug izabren, triggering an initial milestone payment of $250 million due to the advancement of a key clinical trial [1] - The company is advancing its clinical trials in the U.S. and China, with several indications recognized as breakthrough therapies by regulatory agencies [4] - The company aims to commercialize izabren in China by 2026, with expectations for global approval starting in 2029 [4] Group 2 - The innovative drug BL-ARC001 has received clinical trial approval from the National Medical Products Administration (NMPA), showcasing the company's commitment to addressing unmet clinical needs [2] - The funds raised from the recent private placement will be directed entirely towards the development of innovative drug projects, enhancing the company's product pipeline [3] - 百利天恒 is conducting multiple clinical trials for various cancer types, including triple-negative breast cancer and EGFR-mutant non-small cell lung cancer [4]