Core Viewpoint - Ankylosing Spondylitis (AS) predominantly affects young males, and early diagnosis and standardized treatment are crucial to prevent disability [1][2][3] Group 1: Disease Characteristics - AS is a chronic inflammatory disease that leads to inflammation at the tendon insertion points of the spine, resulting in fibrosis and calcification, which can cause spinal stiffness [1] - The incidence of AS is relatively low in China, but the total number of patients is significant, with a male-to-female ratio of 2:1 to 3:1, and the peak age of onset is between 20 and 30 years [2] - Common symptoms include pain in the neck, chest, lower back, buttocks, hips, and large joints, with severe cases leading to spinal deformities and stiffness [2][3] Group 2: Diagnosis and Treatment - The average delay in diagnosis from the onset of symptoms to confirmation can take several years, often due to patients' lack of awareness about AS [3] - Early diagnosis is critical as there are currently no medications that can reverse joint deformities already present in AS patients [3] - Treatment options include non-drug therapies such as exercise, non-steroidal anti-inflammatory drugs (NSAIDs), traditional disease-modifying antirheumatic drugs (DMARDs), and biological agents like Adalimumab [5][6] Group 3: Patient Management and Education - Patients are encouraged to engage in daily physical activities, starting with low-intensity exercises to improve joint function and prevent stiffness [4][6] - Smoking is identified as a risk factor that can worsen AS symptoms, and quitting smoking is recommended for better outcomes [6] - Maintaining a positive mindset is emphasized as it can enhance the effectiveness of standardized treatment [6]
专家：强直性脊柱炎“偏爱”年轻男士 早诊、规范治疗避免致残
Zhong Guo Xin Wen Wang·2025-10-13 05:57