养猪户“仔猪保活”难题有解！内蒙古自治区科技“突围”工程重点项目在呼和浩特正式启动

Core Viewpoint - The launch of the mRNA vaccine project for pig diarrhea represents a significant advancement in addressing a long-standing issue in the pig farming industry, aiming to reduce high mortality rates in piglets and enhance the sustainability of the industry [1][2]. Group 1: Project Overview - The project, led by Jinyu Baoling Biological Pharmaceutical Co., in collaboration with several academic institutions, aims to develop a multi-valent mRNA vaccine targeting major pathogens causing viral diarrhea in pigs [1][2]. - The initiative is part of a regional technology breakthrough project, which seeks to provide new solutions for pig farmers facing challenges with piglet survival [1]. Group 2: Industry Challenges - Viral diarrhea in piglets has been a persistent problem, leading to high mortality rates and impacting the sustainable development of China's pig farming industry [1]. - Traditional vaccines have struggled to keep pace with the rapid mutation of viruses, resulting in insufficient immunogenicity and safety concerns [1]. Group 3: Technological Advancements - The mRNA vaccine technology offers a promising alternative due to its rapid response and efficient expression capabilities, addressing the shortcomings of traditional vaccines [1][2]. - The project aims to develop a proprietary three-valent six-component mRNA vaccine targeting porcine epidemic diarrhea virus, rotavirus, and porcine deltacoronavirus, filling a gap in the market where no similar vaccines are currently available [2]. Group 4: Project Goals and Economic Impact - The project will focus on overcoming four core technical challenges to facilitate the transition of the vaccine from laboratory to industrial application, ultimately establishing a leading platform for mRNA vaccine development and production for pigs [3]. - The successful implementation of this project is expected to reduce economic losses in the livestock industry by billions annually, supporting the healthy development of the pig farming sector and enhancing biosecurity measures [3].