Dow Dips Over 100 Points; US Crude Oil Inventories Surge

Market Overview - U.S. stocks traded lower, with the Dow Jones index falling more than 100 points, down 0.30% to 46,113.98, NASDAQ down 0.21% to 22,622.73, and S&P 500 down 0.34% to 6,648.52 [1] - Real estate shares increased by 0.5%, while financial stocks decreased by 1.5% [1] Commodities - Oil prices rose by 0.1% to $58.32, gold increased by 2.3% to $4,296.60, silver surged by 4.2% to $53.515, while copper fell by 0.1% to $5.0115 [5] European Markets - European shares showed positive movement, with the eurozone's STOXX 600 up 0.69%, Spain's IBEX 35 up 0.48%, London's FTSE 100 up 0.12%, Germany's DAX 40 up 0.38%, and France's CAC 40 up 1.38% [6] Asian Markets - Asian markets closed mostly higher, with Japan's Nikkei 225 up 1.27%, Hong Kong's Hang Seng down 0.09%, China's Shanghai Composite up 0.10%, and India's BSE Sensex up 1.04% [7] Company Performance - Praxis Precision Medicines Inc shares surged 208% to $176.74 following positive Phase 3 results for ulixacaltamide [9] - J.B. Hunt Transport Services, Inc. shares rose 20% to $166.65 after better-than-expected quarterly results and multiple price target increases [9] - Mira Pharmaceuticals Inc shares increased by 57% to $2.07 after announcing new preclinical data [9] - UTime Ltd shares dropped 88% to $0.1496 after a $25 million registered direct offering [9] - Theriva Biologics Inc shares fell 46% to $0.4495 due to a $4 million warrant inducement agreement [9] - Hyperfine Inc shares decreased by 41% to $1.3050 after announcing a $17.5 million public offering [9] Economic Indicators - The Philadelphia Fed Manufacturing Index declined to -12.8 in October from 23.2 in the previous month, missing market estimates of 10 [11] - U.S. crude oil inventories surged by 3.524 million barrels, significantly exceeding market estimates of a 0.12 million gain [11] - U.S. natural-gas stocks rose by 80 billion cubic feet [11]