最高交易总额15.3亿美元,罗氏引进翰森制药新药

Core Insights - Hansoh Pharmaceutical has entered into a licensing agreement with Roche Group's subsidiary, granting exclusive global rights for HS-20110 outside of mainland China, with an upfront payment of $80 million and potential milestone payments of up to $1.45 billion [1] - The asset HS-20110 is an investigational CDH17-targeted antibody-drug conjugate aimed at the gastrointestinal tumor market, currently undergoing Phase I clinical trials for colorectal cancer and other solid tumors in China and the US [1][2] - Hansoh has a strong track record in licensing agreements, having previously licensed two other ADC drugs to GSK in 2023, with upfront payments totaling $24.35 million and potential milestone payments exceeding $30 billion [1][2] Company Performance - As of June 2023, Hansoh Pharmaceutical has achieved over $7 billion in total licensing agreements, reflecting its robust innovation strategy initiated in 2002 [2] - The company reported a revenue of 7.434 billion yuan in the first half of 2023, a year-on-year increase of 14.3%, with a profit of 3.135 billion yuan, up 15.0% [2] - Revenue from innovative drugs and collaborative product sales reached 6.145 billion yuan, representing a 22.1% increase and accounting for 82.7% of total revenue [2] Research and Development - Hansoh has over 70 ongoing clinical trials for innovative drugs, including more than 40 candidate drugs, indicating a strong pipeline [2] - The company's R&D expenditure for the first half of 2023 was approximately 1.441 billion yuan, a 20.4% increase year-on-year, constituting about 19.4% of total revenue [2]