新型眼部植入系统帮助黄斑变性失明患者恢复视力

Core Insights - A new eye implant system has been developed that can help 80% of patients with age-related macular degeneration partially regain their vision [1][2] - Age-related macular degeneration is the leading cause of blindness globally, particularly affecting individuals over 60 years old [1] - The system, named Prima, consists of a retinal implant and augmented reality glasses, designed to replace lost photoreceptor cells due to the disease [2] Group 1 - The Prima system includes a 2mm x 2mm retinal implant that is 30 micrometers thick, which is surgically placed beneath the retina [2] - The augmented reality glasses are equipped with a mini camera that captures images and processes them through a computer to enhance contrast and brightness before projecting them as infrared light onto the retinal implant [2] - Clinical trials involved 38 patients with severe vision impairment, with 32 completing the study [2] Group 2 - After one year of using the Prima system, 81% of participants could read at least 10 more letters on a vision chart, and 78% could read at least 15 more letters [2] - The best-performing participant was able to read 59 additional letters, and 84.4% of participants reported being able to read letters, numbers, and words [2] - A total of 26 serious adverse events were observed among 19 participants, all of which were anticipated risks, including high intraocular pressure and subretinal hemorrhage, with most resolving on their own or through medical intervention [2]