WANTAI BIOLOGICAL(SH:603392) Nan Fang Du Shi Bao·2025-10-21 10:30Core Viewpoint - The first domestic nine-valent HPV vaccine in China has been administered in Shenzhen, marking a significant step in the country's ability to independently supply high-quality HPV vaccines, making China the second country globally to achieve this milestone [1][6]. Group 1: HPV Vaccine Introduction - The nine-valent HPV vaccine is approved for women aged 9 to 45, targeting two peak infection age groups: under 25 and 40-44 [6]. - The vaccine covers nine types of HPV, including seven high-risk types, and offers a reduced dosage schedule for younger girls, requiring only two doses for those aged 9-17, while women aged 18-45 need three doses [6]. - The price of the vaccine is set at 520 yuan per dose, making it more accessible and affordable for the public [6]. Group 2: Cervical Cancer Statistics and Prevention - Cervical cancer poses a significant health threat to women in China, with 151,000 new cases reported in 2022, the highest globally [5]. - The incidence of cervical cancer in China has been rising since 2000, with a trend towards younger age groups, particularly among women under 25 [5]. - HPV is responsible for 99.7% of cervical cancer cases, and vaccination is recognized as one of the safest and most effective preventive measures [5]. Group 3: Vaccine Development and Technology - The nine-valent HPV vaccine was developed by a team led by Academician Xia Ning Shao from Xiamen University in collaboration with Wantai Biological Pharmacy [7]. - The vaccine utilizes a globally innovative E. coli virus-like particle expression technology platform, overcoming long-standing technical barriers and establishing a complete system of independent intellectual property rights [7]. Group 4: Expert Recommendations - Experts emphasize the importance of vaccination to prevent persistent HPV infections, which are a significant risk factor for cervical cancer [7]. - It is recommended that eligible women, especially girls aged 9-14, should receive the HPV vaccine to protect themselves effectively [6][7].