Benzinga·2025-10-21 12:16Summary of Key Points Core Viewpoint - U.S. stock futures showed slight gains, with the Dow futures increasing by approximately 0.1% on Tuesday, while several companies experienced significant declines in pre-market trading due to disappointing earnings or other negative news [1]. Company-Specific Summaries - PACCAR Inc (NASDAQ:PCAR): - Shares fell 18.3% to $7.64 after reporting third-quarter earnings of $1.12 per share, missing the analyst consensus estimate of $1.17 per share. - Quarterly sales were reported at $6.107 billion, also below the consensus estimate of $6.371 billion [1]. - Neuphoria Therapeutics Inc (NASDAQ:NEUP): - Shares dropped 65.3% to $5.35 following the failure of its AFFIRM-1 trial for social anxiety to meet endpoints [4]. - Citius Pharmaceuticals Inc (NASDAQ:CTXR): - Shares decreased by 18.2% to $1.48 after announcing a $6 million registered direct offering [4]. - Galapagos NV – ADR (NASDAQ:GLPG): - Shares declined 15.4% to $28.99 as the company announced plans to wind down its Cell Therapy Business as part of a transformation strategy [4]. - Silvercorp Metals Inc (NYSE:SVM): - Shares fell 9.9% to $6.35 in pre-market trading [4]. - Theravance Biopharma Inc (NASDAQ:TBPH): - Shares decreased by 8.6% to $13.07 [4]. - Pacira Biosciences Inc (NASDAQ:PCRX): - Shares dipped 8.3% to $21.10; the company is set to present new data from a Phase 1 clinical trial for a gene therapy candidate at an upcoming meeting [4]. - Coeur Mining Inc (NYSE:CDE): - Shares fell 8.2% to $20.22 after a previous gain of 5% on Monday [4]. - Endeavour Silver Corp (NYSE:EXK): - Shares declined 8.2% to $8.57 [4]. - Sibanye Stillwater Ltd (NYSE:SBSW): - Shares fell 8.1% to $10.67 [4]. - First Majestic Silver Corp (NYSE:AG): - Shares declined 7.9% to $13.22 [4]. - Hycroft Mining Holding Corporation (NYSE:HYMC): - Shares dipped 7.7% to $8.03 [4]. - Harmony Gold Mining Company Ltd (NYSE:HMY): - Shares declined 6.8% to $18.85 [4]. - Pan American Silver Corp (NYSE:PAAS): - Shares fell 6.6% to $36.80 [4].