Microsoft upgraded, Harley-Davidson downgraded: Wall Street's top analyst calls

Upgrades - Wells Fargo upgraded Glaukos (GKOS) to Overweight from Equal Weight with a price target of $120, up from $92, highlighting the potential of Epioxa as a significant growth driver [2] - RBC Capital upgraded Honeywell (HON) to Outperform from Sector Perform with a price target of $253, up from $235, citing a solid Q3 and the start of a breakup catalyst-rich phase [3] - Truist upgraded Booking Holdings (BKNG) to Buy from Hold with a price target of $5,750, up from $5,630, based on Asia's long-term travel outlook and steady global GDP growth [3] - JPMorgan upgraded Five Below (FIVE) to Overweight from Neutral with a price target of $186, up from $154, anticipating multi-year earnings growth supported by unit growth expansion [4] - Guggenheim upgraded Microsoft (MSFT) to Buy from Neutral with a price target of $586, believing the company will benefit from the artificial intelligence sector [5] Downgrades - Keefe Bruyette downgraded Berkshire Hathaway (BRK.A) to Underperform from Market Perform with a price target of $7,000, down from $735,000, due to concerns over Geico's underwriting margin and other economic pressures [5] - Morgan Stanley downgraded Harley-Davidson (HOG) to Underweight from Equal Weight with a price target of $25, down from $27, indicating a 10% downside potential [5] - RBC Capital downgraded Roper Technologies (ROP) to Sector Perform from Outperform with a price target of $539, down from $644, citing limited relative upside [5] - Jefferies downgraded Keysight Technologies (KEYS) to Hold from Buy with a price target of $180, down from $181, noting that the stock's valuation reflects its growth potential [5] - Williams Trading downgraded Wolverine World Wide (WWW) to Hold from Buy with a price target of $27, down from $30, expecting a deceleration in Saucony's sales growth [5]