Bio-Techne(US:TECH) Prnewswire·2025-10-28 10:30Core Insights - Bio-Techne Corporation has launched the ProximityScope assay, a spatial solution that integrates with the BOND RX staining platform from Leica Biosystems, enabling visualization of functional protein-protein interactions on fixed tissue with subcellular resolution [1][2][4] Product Features - The ProximityScope assay provides a visual signal only when two proteins are in close proximity, offering insights into biological mechanisms that were previously inaccessible [2] - It works in conjunction with the BOND RX staining system and ACD's RNAscope Multiomic LS kit, allowing for enhanced detection of RNA and protein on the same tissue section [2] - The assay combines high sensitivity, specificity, and low background, addressing limitations of traditional methods like bulk pull-down assays [3] Applications - Key applications include visualizing cell-cell interactions for immune checkpoint studies, analyzing cell surface interactions that activate signaling pathways, evaluating antibody-based therapeutics, and investigating intracellular interactions related to transcriptional activation [4] Industry Context - The ProximityScope assay represents a significant advancement in spatial biology, providing researchers with a powerful automated solution to decode complex biological systems and accelerate therapeutic innovation [3][4] - Bio-Techne generated over $1.2 billion in net sales in fiscal 2025, indicating strong market presence and demand for innovative life science tools [6]