道指开盘跌0.4%，标普500跌0.5%，纳指跌0.4%

Group 1 - Meta experienced a significant decline of 10.4% due to a one-time tax expense that led to a sharp drop in quarterly profits [1] - Microsoft saw a decrease of 2.3%, despite exceeding expectations in Q1 performance [1] - Alphabet's stock rose by 7.3%, with Q3 revenue, profit, and full-year capital expenditure guidance all surpassing expectations [1] Group 2 - Metsera's stock surged by 20.2% following Novo Nordisk's proposal to acquire the company at $56.50 per share [1]