中国7部门发文：将HPV疫苗纳入国家免疫规划

Group 1 - The Chinese government has decided to include the HPV vaccine in the national immunization program starting from November 10, 2025, targeting girls born after November 10, 2011, who are 13 years old, providing them with two doses of the bivalent HPV vaccine for free [1][2] - The decision is based on the rising incidence and mortality rates of cervical cancer in China, particularly among younger populations, highlighting the importance of HPV vaccination in preventing high-risk HPV infections and reducing the occurrence of cervical cancer [1][2] - The World Health Organization recommends vaccinating girls aged 9 to 14 years before they become sexually active, while China has set the target group for free vaccination at 13 years old, considering the optimal balance of protection effectiveness, cost-effectiveness, and operational feasibility [1][2] Group 2 - The notification emphasizes the need for monitoring the production and supply of HPV vaccines, with various departments responsible for ensuring stable production and addressing challenges faced by manufacturers [2] - China has a total annual production capacity of 55 million doses of the bivalent HPV vaccine from two domestic manufacturers, which is sufficient to meet market demand, and these vaccines have received pre-certification from the World Health Organization [2] - The first domestically produced nine-valent HPV vaccine was approved for market use in mid-2023, marking it as the second nine-valent HPV vaccine globally and breaking the long-standing market monopoly held by foreign products [2]