Shang Hai Zheng Quan Bao·2025-10-30 23:17Core Viewpoint - Shanghai Pharmaceuticals has demonstrated resilience in its financial performance, achieving a net profit increase driven by accounting changes, while also focusing on innovative drug development and expanding its market presence in traditional Chinese medicine [3][4][11]. Financial Performance - For the first nine months of 2025, the company reported a total revenue of CNY 215.07 billion, a year-on-year increase of 2.60% [3]. - The net profit attributable to shareholders reached CNY 5.15 billion, reflecting a significant year-on-year growth of 26.96%, primarily due to a one-time special gain from accounting changes [3]. - Excluding one-time items, the adjusted net profit was CNY 3.98 billion, showing a slight decline of 1.85% year-on-year [3][4]. - The operating cash flow for the period was CNY 2.35 billion, indicating sustained high-quality development [4]. Business Highlights - The company ranked among the top ten in the "2024 Annual Top 100 Pharmaceutical Enterprises in China" and improved its MSCI ESG rating to AA [3]. - Research and development investments totaled CNY 1.73 billion, accounting for 9.52% of pharmaceutical industrial sales revenue [4]. - The company has 57 new drug candidates in clinical trials, including 45 innovative drugs [4]. Drug Development - The BCD-085 project, an innovative monoclonal antibody targeting IL-17, has submitted a new drug application for ankylosing spondylitis [5]. - The company is advancing the clinical trials for its traditional Chinese medicine, Shenqi Shiru Wan, aimed at treating cervical spondylotic myelopathy [5]. - The B019 project, a CAR-T cell therapy targeting CD19 and CD22, is in the I phase of clinical trials for acute lymphoblastic leukemia and lymphoma [6]. Traditional Chinese Medicine Development - The company is enhancing its core competitiveness through the secondary development of major traditional Chinese medicine products [7]. - Significant progress has been made in clinical trials for products like Weifuchun and Daning Pian, with expert consensus published for their clinical applications [8][9]. International Expansion - The company has successfully exported its products, including Zhenqi Pian and Daning Pian, to Canada, marking a significant step in the internationalization of traditional Chinese medicine [10]. Social Responsibility - Shanghai Pharmaceuticals is committed to rare disease treatment, establishing a collaborative ecosystem to enhance the accessibility of rare disease medications [11]. - The company has 51 products in the rare disease treatment pipeline, covering 67 rare disease conditions [11]. Commercial Growth - The pharmaceutical commercial business continues to show resilience, with innovative drug sales reaching CNY 40.7 billion, a growth of over 25% [12][13]. - The import agency business achieved sales of CNY 27.6 billion, growing by over 14% [14]. - The medical device health business reported sales of CNY 33.99 billion, with a growth of over 4% [14].