国际最新健康研究：日行5000步或助减缓阿尔茨海默病相关衰退

Core Insights - A recent study published in the journal Nature Medicine indicates that walking more than 5,000 steps daily may help slow cognitive decline associated with Alzheimer's disease, particularly by reducing tau protein accumulation [1][2][3] Group 1: Research Findings - The study tracked 294 cognitively healthy older adults (ages 50-90) over 14 years, utilizing pedometer data and PET imaging to assess amyloid and tau protein levels [2] - Increased physical activity was linked to a slower rate of cognitive decline related to amyloid plaques, with a specific focus on tau protein accumulation rather than amyloid pathology [2] - Moderate activity levels (5,001-7,500 steps daily) were associated with stable tau protein levels and cognitive function, while even light activity (3,001-5,000 steps) showed significant benefits in slowing tau accumulation and cognitive decline [2][3] Group 2: Implications for Older Adults - The findings suggest that increasing physical activity could be a viable strategy to delay the pathological changes and cognitive decline associated with preclinical Alzheimer's disease [3] - The study emphasizes achievable exercise goals for sedentary older adults, especially with the rise of digital wearable devices like smartwatches, which can motivate increased physical activity [3]