Core Insights - Aligos Therapeutics, Inc. reported significant progress in its clinical trials and financial results for Q3 2025, focusing on therapies for liver and viral diseases [1][2]. Recent Business Progress - The Phase 2 B-SUPREME study of pevifoscorvir sodium (pevy) is progressing well, with enrollment across multiple countries including the U.S., China, Hong Kong, and Canada, with interim readouts expected in 2026 [2][7]. - The company is optimistic about the potential of pevifoscorvir sodium as a treatment for chronic hepatitis B virus (HBV) infection and is also advancing its pipeline, including ALG-055009 for obesity and MASH [3][4]. Financial Results for Q3 2025 - Cash, cash equivalents, and investments totaled $99.1 million as of September 30, 2025, up from $56.9 million at the end of 2024, providing sufficient funding for operations into Q3 2026 [5]. - The net loss for Q3 2025 was $31.5 million, or $(3.04) per share, compared to a net loss of $19.3 million, or $(3.07) per share, in Q3 2024 [6][16]. Research and Development Expenses - R&D expenses for Q3 2025 were $23.9 million, an increase from $16.8 million in the same period of 2024, primarily due to costs associated with the pevifoscorvir sodium Phase 2a clinical trial [8]. - General and administrative expenses rose to $5.2 million in Q3 2025 from $4.6 million in Q3 2024, mainly due to increased legal and related expenses [9]. Other Financial Metrics - Interest and other income remained stable at $1.1 million for both Q3 2025 and Q3 2024, while the change in fair value of common warrants resulted in a loss of $4.2 million in Q3 2025, compared to a loss of $0.1 million in Q3 2024 [10][16].
Aligos Therapeutics Reports Recent Business Progress and Third Quarter 2025 Financial Results