新研究从药物生产中意外发现超强抗生素

Core Insights - Researchers have discovered a promising new antibiotic, pre-penicillin C lactone, which is effective against "superbugs" resistant to multiple antibiotics, including methicillin-resistant Staphylococcus aureus (MRSA) [1][2] Group 1: Research Findings - The antibiotic pre-penicillin C lactone was found during the production process of the commonly used antibiotic penicillin A, and it exhibits over 100 times higher antibacterial activity against various Gram-positive bacteria compared to penicillin A [1] - This discovery highlights the potential of identifying and testing intermediates in the synthesis pathways of natural compounds to find new antibiotics that can effectively combat antibiotic resistance [1] Group 2: Academic Collaboration - The research was conducted by Monash University in collaboration with the University of Warwick in the UK, indicating a strong international partnership in addressing antibiotic resistance [1]