流感毒株已发生变化，高峰可能出现在12月中下旬和1月初

Group 1 - The peak of influenza epidemic in China is expected to occur in late December and early January [1] - Shanghai is entering the influenza epidemic season with a rising positive detection rate of influenza [1] - The dominant influenza strain has shifted from H1N1 to H3N2 in Shanghai [1] Group 2 - Current influenza strains remain highly sensitive to antiviral medications such as oseltamivir and baloxavir [1] - Hospitals in Shanghai report sufficient drug supplies to handle the upcoming respiratory infection season [1] - Azithromycin, previously in short supply, is now stable in supply for treating mycoplasma infections [1] Group 3 - Prices for antiviral drugs like baloxavir have remained stable this year, with 40mg tablets priced around 200 yuan [2] - Two domestic antiviral drugs, Isunavir and Jike Shou, have been approved, offering similar mechanisms to baloxavir [2] - The resistance mutation rates for Isunavir against H1N1 and H3N2 are low, indicating a low risk of resistance [2]